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Every year, 800.000 babies are born extremely preterm (<28 weeks of age) worldwide. These infants are usually transferred to an air-based neonatal intensive care unit to support their heart and lung development. Exposure to air, however, leads to many complications, because the lungs are not fully developed yet. The perinatal life support (PLS) project aims to develop a novel, alternative environment,more similar to the mother’s womb. In this PLS system, extremely premature babies would be transferred to an environment where the lungs remain filled with fluid and the umbilical cord will be attached to an artificial placenta to improve their organ development and ease the transition to newborn life. This project aims to increase the chances of survival for extremely premature babies and not to change the viability threshold.

Project

Project

In this section you will find information about the background and approach of the PLS project

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Consortium partners

Consortium partners

In this section you will find information about the background and approach of the PLS project

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Families

Families

In this section you will find relevant information for families.

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Get to know Juno!

Get to know Juno! Juno Perinatal Healthcare is a spin-off company of and companion to the PLS project. The startup was founded in July 2021 by engineers Jasmijn and Lyla Kok, medical engineer Beatrijs van der Hout, technician physician dr. Myrthe van der Ven, and Gynecologist prof. dr. Guid Oei. Juno aims to ensure that…

PLS Explained: The Animation

PLS Explained: The Animation Explaining how the PLS project works in under 3 minutes is a challenge, but it is possible! This animation shows the PLS mission, the problem that the researchers are taking on, and how they aim to solve it – all in understandable wording. It can be shown to anyone who is…

POLIMI at European Conference on Biomedical Optics

POLIMI at European Conference on Biomedical Optics Caterina Amendola from POLIMI will be speaking at the European Conference on Biomedical Optics! The presentation is on the same topic as their recent paper: Sensitivity of TD-NIRS in Estimating Neonatal Cerebral Hemodynamics with Homogenous Models of Analysis. The conference will take place online, from 20-24 June 2021.…

New publication

Accuracy of homogeneous models for photon diffusion in estimating neonatal cerebral hemodynamics by TD-NIRS Authors: Amendola, Caterina; Spinelli, Lorenzo; Contini, Davide; De Carli, Agnese; Martinelli, Cesare; Fumagalli, Monica; Torricelli, Alessandro.  Abstract: We assessed the accuracy of homogenous (semi-infinite, spherical) photon diffusion models in estimating absolute hemodynamic parameters of the neonatal brain in realistic scenarios (ischemia,…

PLS at EPNIC conference

PLS at ESPNIC conference Two PLS abstracts accepted by ESPNIC conference Two abstracts are accepted by the ESPNIC (The European Society of Paediatric and Neonatal Intensive Care) conference, which is hosted online at 15-18 June . The follwing abstracts are submitted: – ‘Towards a Premature Fetal Manikin for Model-Driven Simulation to Validate Perinatal Life Support…

News item in Leaps.org

Leaps.org: Artificial Wombs Are Getting Closer to Reality for Premature Babies – Stav Dimitropoulos – 23 September 2020 – The PLS consortium created a mannequin of 24 weeks-old fetus replicated from MR imaging. Leaps.org published an interesting news item about the mannequin. Read the news item here.

News item in ‘Het Financieele Dagblad’

Het Financieele Dagblad: Artificial uterus must fool fetus article. –Lex Rietman – 13 February 2021- The Netherlands is also working on the development of an artificial uterus. The TU/e – together with universities from Aachen and Milan – received a subsidy of € 2.90 million from the EU H2020 program for this. One of the…

PLS-complimentary project Juno

PLS-complimentary project Juno Perinatal Healthcare was awarded one of five Eindhoven Engine innovation projects Article translated and adapted from Linkmagazine (Dutch) With an investment of more than € 2.2 million, various innovative challenging projects with potential impact on society and the economy are given additional funds from Eindhoven Engine. Together these projects represent an investment of…

Consortium meeting

First consortium meeting of the international project “Perinatal Life Support” On the 2nd of June, the first consortium meeting of the international project “Perinatal Life Support (PLS)” was held. Due to the current circumstances, the consortium meeting was held via teleconference. The PLS project aims to develop an artificial womb to increase the chances of…